Description. It is also incompatible with metal compounds and surface active materials. CAS 822-06-0, EC Number 212-485-8, chemical formula OCN (CH)NCO. Less widely used, but still important, are the aliphatic diisocyanates, including hexamethylene diisocyanate (HDI . Any other relevant safety information that may be available. 1,6-Diisocyanatohexane. Chemsrc provides POLY(HEXAMETHYLENE DIISOCYANATE)(CAS#:28182-81-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Hexamethylene diisocyanate, 2,4-toluene diisocyanate, 2,6-to-luene diisocyanate, isophorone diisocyanate and 4,4-methylene . All Hazards GreenScreen Hazards Only Pharos Hazards C2C Hazards. This chemical is incompatible with strong bases, amines, acids and strong oxidizers. Hazard statements (GHS-US) : H315 - Causes skin irritation H317 - May cause an allergic skin reaction H319 - Causes serious eye irritation H330 - Fatal if inhaled . To avoid the hazard problems derived from NMP containing dispersions, the process evolved into the modified prepolymer method. f Exposure to Hexamethylene Diisocyanate can cause headache, dizziness, nausea and vomiting. Authority: 21 U.S.C. Hexamethylene diisocyanate. CAS No. Hexamethylene Diisocyanate (HDI) Polymers as Used in Cosmetics Status: Draft Tentative Report for Panel Review Release Date: November 20, 2015 Panel Meeting Date: December 14-15, 2015 . Hexamethylene diisocyanate (HDI) is an important chemical building block in the production of high value-added polyurethane because of its some excellent properties. 15, 1977, unless otherwise noted. The Environmental Protection Agency (EPA) identifies the most serious hazardous waste sites in the nation. Hexamethylene Diisocyanate 822-06- Hazard Summary Hexamethylene diisocyanate is used as a polymerizing agent in polyurethane paints and coatings. NIOSH Pocket Guide to Chemical Hazards - Hexamethylene diisocyanate This page was last edited on 28 August 2022, at 03:53 (UTC). Biuret hexamethylene diisocyanate | C10H17N5O4 | CID 18355665 - structure, chemical names, physical and chemical properties, classification, patents, literature . CAS No. Request Assessment The National Institute for Occupational Safety and Health (NIOSH) requests assistance in preventing asthma, other respiratory disease, and death from diisocyanate exposure. Hexamethylene Diisocyanate. Clear light yellow liquid; Nearly odorless; [Bayer Material Science MSDS] Sources/Uses. 2,4-Toluene diisocyanate. Safety Assessment of Hexamethylene Diisocyanate (HDI) Polymers as Used in Cosmetics Status: Draft Final Report for Panel Review Release Date: March 7, 2016 Panel Meeting Date: March 31- April 1, 2016 The 2016 Cosmetic Ingredient Review Expert Panel members are: Chair, Wilma F. Bergfeld, M.D., F.A.C.P. CAS No . PDF Version [128 KB] This fact sheet answers the most frequently asked health questions about hexamethylene diisocyanate. Hexamethylene diisocyanate hazards Morel CM, Gendre M, Cavigneax A, et al. These sites make up the National Priorities List (NPL . 3702), 153.1, and 154.5. Isocyanates and thioisocyanates, such as 2,2,4-TRIMETHYLHEXAMETHYLENE DIISOCYANATE, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. H335 May cause respiratory irritation. It is an industrial chemical that is not known to occur naturally. Other names HDI 1,6-hexane diisocyanate. The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. Physical Form. Acute (short-term) exposure to high concentrations of hexamethylene diisocyanate in humans can cause pulmonary edema, coughing, and shortness of breath. Articles of POLY(HEXAMETHYLENE DIISOCYANATE) are included as well. For more information, call the ATSDR Information Center at 1-888-422-8737. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS. NIOSH: Preventing Asthma and Death from Diisocyanate Exposure. Methyl Isocyanate. Chronic Health Effects The following chronic (long-term) health effects can occur at some time after exposure to Hexamethylene Diisocyanate and can last for months or years: Cancer Hazard f There is no evidence that Hexamethylene Diisocyanate Base-catalyzed reactions of this compound with alcohols may be explosively violent in the absence of diluting solvents. The Foundation for Occupational Health & Safety (FOHS) is a 501(c)(3) corporation fostering the expanded establishment of occupational exposure values throughout the world. HEXAMETHYLENE DIISOCYANATE. Hexamethylene diisocyanate (822-06-0) is an aliphatic diisocyanate monomer typically used to produce oligomers and prepolymers that when combined with a polyol produce a light-stable polyurethane. . permatex water pump and thermostat housing gasket maker. It is also commonly known as HDI, 1,6-hexamethylene diisocyanate, 1,6-diisocyanatohexane, Mondur HX, and Desmodur H. Hexamethylene diisocyanate is mainly used to make polyurethane foams and coatings. Hazard Recognition. Up to 0.125 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode*. HEXAMETHYLENE DIISOCYANATE: ICSC: 0278 (April 2017) HMDI 1,6-Hexamethylene diisocyanate 1,6-Diisocyanatohexane: CAS #: 822-06-0: UN #: 2281 EC Number: 212-485-8 ACUTE HAZARDS PREVENTION FIRE FIGHTING; FIRE & EXPLOSION: Combustible under specific conditions. NO open flames. 98.0% (GC) Chemical Name or Material. Hexamethylene Diisocyanate - Nature. . Hexamethylene diisocyanate | C8H12N2O2 | CID 13192 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . 822066. Base-catalyzed reactions of this compound with alcohols may be explosively violent in the absence of diluting solvents. Hexamethylene Diisocyanate 822-06- Hazard Summary Hexamethylene diisocyanate is used as a polymerizing agent in polyurethane paints and coatings. This chemical is incompatible with strong bases, amines, acids and strong oxidizers. Factory areaXuzhou City, Jiangsu Province, China; Whatsapp: +8619961957599 (CEOJoyce) Whatsapp: +8613805212761 (General Manager:Athena) Email: info@mit-ivy.com The Occupational Safety and Health Administration's (OSHA) permissible-exposure limit (PEL) for TDI and MDI is 0.02 part per million (ppm) in air as a ceiling limit (C). Hexamethylene diisocyanate Names Preferred IUPAC name. Precautionary statement (s) Prevention. The EWG VERIFIED mark means a product meets EWG's strictest criteria for transparency and health. This fact sheet is one in a series of . HEXAMETHYLENE DIISOCYANATE. ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Hexamethylene diisocyanate. T. Share Profile ALSO CALLED 1,6-diisocyanato hexane, 1,6-diisocyanato-hexane, 1,6-Diisocyanatohexane, 1,6-HEXAMETHYLENE DIISOCYA . ToxFAQs TM for Hexamethylene Diisocyanate (HDI) Spanish: Diisocianato de hexametileno. Synonyms: HDI. 822-06-. 1981. Diisocyanates are a family of chemical building blocks used to make a wide range of polyurethane products. Formula Weight. SAFETY DATA SHEET Version 6.5 Revision Date 06/27/2022 Print Date 09/17/2022 . Low toxicity by inhalation. Deutschland Tel. 2281. 822-06- . Risk Statements : 43-42/43-20. Information about preventing adverse health effects from . However, the total number of NPL sites evaluated is not . Traditionally, the HDI synthesis route involves extremely toxic phosgene as an industrial scale reagent. : 28182-81-2 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Synthesis of substances 1.3 . UNUSUAL FIRE AND EXPLOSION HAZARDS: No unusual fire or explosion hazards noted. The Environmental Protection Agency (EPA) identifies the most serious hazardous waste sites in the nation. Hexamethylene diisocyanate for synthesis. Safety Data Sheet for Hexamethylene diisocyanate 822066. Hazard classification & labelling Hazard classification and labelling The 'Hazard classification and labelling' section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. - Skin corrosion/irritation Based on available data, the classification criteria are not met.. - Serious eye damage/irritation Based on available data, the classification criteria are These sites make up the National Priorities List (NPL) and are the sites targeted for long-term federal clean-up . Material Safety Data Sheet or SDS for Hexamethylene diisocyanate 822066 from Merck for download or viewing in the browser. Use powder . Hazard score. Get to learn about Hexamethylene diisocyanate. The nonbiodegradable and other hazards associated with the plastic packaging have led to a renewed interest in . Hexamethylene diisocyanate is also extremely Hexamethylene Diisocyanate. 4,4'-Methylenediphenyl Diisocyanate (MDI). +49 34291 3372-39 contact@hpc-standards.com: HAZARDS IDENTIFICATION: 2.1 Classification of the substance or mixture Classification according to Regulation . This proposed rule would apply to the carriage of the cargoes from the tank vessel population described in 46 CFR 30.01-5, 150.110 (with exceptions outlined in 46 U.S.C. At room temperature, the relative density is about 1.05, the boiling point is about 255~261 , and the melting point (freezing point) is -67 ~-55 . Product name : Poly(hexamethylene diisocyanate) Product Number : 418005 Brand : Aldrich CAS-No. 1,6-hexamethylene diisocyanate.Hazard Summary.Cahiers de Notes Documentaires 105 633-636. Slightly soluble in water, react slowly in water. Acute (short-term) exposure to high concentrations of hexamethylene-1,6-diisocyanate in humans can cause pulmonary edema, coughing, and shortness of breath.Hexamethylene-1,6-diisocyanate is also extremely irritating to the eyes, nose, and throat. Select Language. Hexamethylene diisocyanate (HDI), the focus of this study, is one of the most commonly used diisocyanates and is employed in autobody spray paints, the manufacture of spinnable fibers, and the preservation of animal hides (4). Relevant identified uses of the substance or mixture and uses advised against 2022 Liquid Chemical Categorization Updates, 57984-58018 [2022-18798] Download as PDF September, 2015 - Insufficient Data Announcement. HEXAMETHYLENE DIISOCYANATE POLYMER Safety Profile. Source: 42 FR 14572, Mar. Many workers are unaware of the potential hazards that chemicals present in their work environment, which makes them more vulnerable to injury. Hexamethylene Diisocyanate. Hexamethylene-1,6-Diisocyanate (822-06-0) ; Human studies have suggested that chronic (long-term) exposure to hexamethylene-1,6-diisocyanate may cause chronic lung problems . safety equipment such as a respirator or mask. The overall knowledge and encyclopedia of Hexamethylene diisocyanate covering characteristics, safety, usage, MSDS/SDS and more. Hazard statement (s) H315 Causes skin irritation. (NTP, 1992). Text is available under the Creative Commons . This Alert summarizes seven case reports of disease and deaths following occupational exposure to diisocyanates. Acute (short-term) exposure to high concentrations of hexamethylene diisocyanate in humans can cause pulmonary edema, coughing, and shortness of breath. 1907/2006 (REACH) Hexamethylene diisocyanate Version number: GHS 1.0 Date of compilation: 2019-09-16 United Kingdom: en Page: 2 / 12 HEXAMETHYLENE DIISOCYANATE reacts with water. (DMBA); sodium dodecyl sulfate (SDS); 1,6-hexamethylene diisocyanate (HDI); L-lysine (LYS); maleated cottonseed oil-based polyol (MAHCSO); aliphatic dihydrazides (DHZ); pyromellitic dianhydride (PMDA); 3,3,4,4 . It is classified as an diisocyanate. during processing, thermal decomposition conditions or unblocking), there is a potential for the release of hexamethylene diisocyanate (HDI) vapors. Hazard Summary. Hexamethylene diisocyanate is a colorless or yellowish liquid with a pungent odor. For more information, you may call the ATSDR Information Center at 1-888-422-8737. ; Donald V. . The ceiling is the . First-Aid Measures FIRST AID - EYE CONTACT: Immediately flush eyes with plenty of water for at least 15 minutes holding eyelids open. H331 Toxic if inhaled. Name of substance Hexamethylene diisocyanate Identifiers CAS No 822-06- EC No 212-485-8 Molecular formula C8H12N2O2 Molar mass 168.2 g/mol Safety Data Sheet according to Regulation (EC) No. Sigma-Aldrich. H317 May cause an allergic skin reaction. Hexamethylene diisocyanate (HDI) is the organic compound with the formula (CH 2) 6 (NCO) 2. The Office of Environmental Health Hazard Assessment (OEHHA) is adopting new Reference Exposure Levels (RELs) for Hexamethylene Diisocyanate (Monomer and Polydiisocyanates) (HDI) for use in the Air Toxics Hot Spots Program. Safety Statements : 36/37-45-23-37-24. RELs are airborne concentrations of a chemical that are not anticipated to result in adverse noncancer health effects for . It is also used as a hardener in automobile and airplane . Editorial Note: Up to 0.25 ppm: (APF = 50) Any self-contained breathing apparatus with a full facepiece. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to . This public health statement tells you about hexamethylene diisocyanate (HDI) and the effects of exposure. If you already have asthma and breathe in respiratory irritants, you may have an asthma attack. Closed containers may explode when . Show PubMed Results. All U.S.- and foreign- flagged tank vessels are included, unless exempted by 46 CFR 30.01-5 or 46 CFR 153.1. H319 Causes serious eye irritation. CAS No. . (DOT) : UN2078 Proper Shipping Name (DOT) : Toluene diisocyanate . Percent Purity. About FOHS. Product Name Hexamethylene diisocyanate. Health & Safety Laboratory, Harpur Hill, Buxton SK17 9JN, United Kingdom 2 Examiner of the method, Currenta GmbH & Co. OHG, CUR-SI-GS-Institute for Biomonitoring, 51368 Le- (Hazard Code and Statement) Acute Tox. For the same safety problems noted above, hexamethylene diisocyanate . Hexamethylene diisocyanate. The following exposure limits for hexamethylene diisocyanate (HDI) do not apply to the product in its supplied form; however, when the product is heated (i.e. Used as an industrial coating; [REPROTOX] Comments. Hexamethylene diisocyanate is a pale yellow liquid with a strong odor. This. 624-83-9. CAS number: 822-06-. Product Name Hexamethylene diisocyanate. EPA: Hazard Summary - Hexamethylene Diisocyanate. A skin and eye irritant. The effects of HDI on airway epithelial cells remain poorly described despite the doc- See annual publication for most recent information. If your safety equipment does not fit right or does not work properly when you are using products that contain HDI, you may be exposed to larger . rabbit rescue maine norwegian cruise. Gives off irritating or toxic fumes (or gases) in a fire. Design & Illustration Clear Liquid at 20C. 3 * 3 (Acute toxicity Category 3) . HEXAMETHYLENE DIISOCYANATE reacts with water. When heated to decomposition it emits toxic vapors of NO x and Cl . Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of . Molecular formula: C 15 H 22 N 2 O 2. Hexamethylene Diisocyanate 822-06- 0.1-1.0 GHS06-GHS08 H311-315-317-319-330-334-335 4. Contains 0.1-0.5% hexamethylene-1,6-diisocyanate (CAS# 822-06-0); Slowly reacts with water evolving carbon dioxide; An irritant that may cause transient corneal injury; May cause skin and . Hexamethylene diisocyanate 822-06- >95 1.0 SARA 311/312 Hazard CategoriesSee section 2 for more information CWA (Clean Water Act) Not applicable Clean Air Act Component HAPS Data Class 1 Ozone DepletorsClass 2 Ozone Depletors Hexamethylene diisocyanate X - OSHA - Occupational Safety and Health Administration Not applicable The most widely used aromatic diisocyanates are toluene diisocyanate (TDI) and methylene diphenyl diisocyanate (MDI). Relevant identified uses of the substance or mixture and uses advised against Relevant identified uses : /PRNewswire/ -- The "Hexamethylene Diisocyanate (CAS 822-06-0): Market Research Report 2019" report has been added to ResearchAndMarkets.com's offering. Contact us to make an appointment at our (YOEMP) Clinic Isocyanates are irritants They irritate the respiratory tract or your skin just as many other substances in body shops do - like acids, ammonia, dusts and solvents. . H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. 101-68-8. 321, 342, 348, 379e. Hazard Codes : Xn,Xi. Catalog Number 822066. NIOSH: Criteria for a Recommended Standard - Occupational Exposure to Diisocyanates.September 1978. UN2078 Toluene diisocyanate, 6.1, II UN-No. Recommended Products Propyl isocyanate SDS Isophorone diisocyanate SDS 1,6-Hexanediol SDS Hexamethylene Diisocyanate SDS ISOCYANIC ACID SDS Tolylene-2,4-diisocyanate SDS 1,4-bis(isocyanatomethyl)cyclohexane SDS 1-Naphthyl isocyanate SDS Catalog Number 822066. Material Safety Data Sheet or SDS for Hexamethylene diisocyanate 822066 from MilliporeSigma for download or viewing in the browser. (hexamethylene diisocyanate)- . Hexamethylene diisocyanate: Catalog No. Safety Data Sheet for Hexamethylene diisocyanate 822066. 168.20. . : 685917: Relevant identified uses of the substance or mixture: Identified: Laboratory chemical uses: R&D . The most common forms of isocyanates are toluene diisocyanate (TDI), methylene diphenyl diisocyanate (MDI) and hexamethylene diisocyanate (HDI). Hexamethylene diisocyanate has not been found in any of the 1,445 current or former NPL sites. Identifiers CAS Number. +49 34291 3372-36 Fax. It is also incompatible with metal compounds and surface active materials. CAS#: 822-06-. :,:Hexamethylene Diisocyanate,CAS:822-06-0,.1,6-.::C8H12N2O2,:168.193,:1.01g/cm 3 ,:-55,:255C at 760 mmHg,:140C,:Reacts,:0.0167mmHg at 25C,:1 . Up to 1 ppm: (APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a . . (APF = 50) Any supplied-air respirator with a full facepiece. Hexamethylene diisocyanate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.